Extended Data Fig. 5: Intrapatient immune heterogeneity.
From: Immune evasion before tumour invasion in early lung squamous carcinogenesis
a, Stacked bars illustrate the relative cellular abundance of different immune-cell types estimated with CIBERSORT, in patients sampled for multiple grades. There are similar profiles for samples from the same grade, independent of the patient. b, Single-sample gene-set enrichment analysis was performed on the HD immune-cell signatures. The heat map represents one-dimensional clustering by immune-cell type, in which the samples of each molecular group were ordered by their average enrichment score. c, A chord diagram links the samples derived from the same patient. The order of the samples is preserved from b.
