Extended Data Fig. 7: ATF6 and IRE1 branches of the UPR are activated in CALR-mutated progenitor cells.
From: Somatic mutations and cell identity linked by Genotyping of Transcriptomes

By sample (ET01–ET05), expression of ATF6-, PERK- and XBP1-target genes in the UPR in CALR wild-type and mutant MkPs and HSPCs (two-sided Wilcoxon rank-sum test).