Extended Data Fig. 10: Top 500 differentially expressed genes.
From: A mutation-independent approach for muscular dystrophy via upregulation of a modifier gene
Heat map illustrating the log-normalized counts per million for the top 500 genes that were differentially expressed in quadriceps isolated from wild-type mice, or dy2j/dy2j mice injected with AAV9s carrying SadCas9–2×VP64 only (no guide, n = 3) or with three guides (three guides, n = 3), and compared to age-matched, untreated dy2j/dy2j mice. Red indicates higher expression; blue indicates lower expression.
