Extended Data Fig. 4: Representative images of Lama1-positive muscle sections.
From: A mutation-independent approach for muscular dystrophy via upregulation of a modifier gene
Three-week-old mice were injected systemically with three guides (n = 5) at the dose of 3 × 1011 viral genomes per gram of mouse (split into two vectors, thus total dose was 2 × 3× 1011 viral genomes per gram of mouse) in the tail vein, and euthanized at the age of 11–12 weeks old. Muscles were stained for Lama1 expression (red). Scale bars, 500 µm. The experiment was repeated three times independently with similar results.
