Extended Data Fig. 4: The regulon sample gene sets.
From: Molecular architecture of lineage allocation and tissue organization in early mouse embryo
a, t-SNE distribution of tissue samples of E2.5 to E7.5 embryos based on regulon-activity scores (n = 226). b, Two-dimensional PCA plots (n = 226) and corn plots showing the averaged regulon activities of G2, G3, G4, G6, G7, G8 and G9 regulon groups. c, The CSI co-expression network analysis (edges were filtered by CSI >0.85) for the nine regulon groups. Edges: positive interaction (brown), negative interaction (green). Triangle nodes denote transcription factors with knockout gastrulation phenotype in MGI database. A wider edge signifies higher correlation. d, The gene-expression profile of lineage markers in the different regulon sample groups.
