Extended Data Fig. 1: Fold antiphage defence conferred by four-gene defence systems against various phages. | Nature

Extended Data Fig. 1: Fold antiphage defence conferred by four-gene defence systems against various phages.

From: Cyclic GMP–AMP signalling protects bacteria against viral infection

Extended Data Fig. 1

The four-gene operon from either V. cholerae El Tor or E. coli TW11681 was cloned into E. coli MG1655 (Methods). Fold antiphage defence, as measured by plaque assays, is shown. The fold defence was calculated as the ratio between the efficiency of plating of the phage on the operon-lacking control strain and the efficiency of plating on the operon-containing strain (Fig. 2b, Methods). Bar graph represents average of three independent replicates, with individual data points overlaid. Points that fall below the x axis (for SECphi17, SECphi18 and SECphi27) denote values lower than 1.

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