Extended Data Fig. 5: The bacterial CBASS functions through abortive infection.
From: Cyclic GMP–AMP signalling protects bacteria against viral infection
a, Growth curves in liquid culture for CBASS-containing and CBASS-lacking (empty vector) bacteria infected by phage SECphi18 at 25 °C. Bacteria were infected at time = 0 at an MOI of 0.02 or 2. Three independent replicates for each MOI are shown, and each curve shows an individual replicate. b, Growth curves in liquid culture for cells containing a minimal CBASS comprising phospholipase–cGAS (capV-dncV) only. Bacteria were infected at time = 0 at an MOI of 2 by phage P1. Three independent replicates for each MOI are shown, and each curve shows an individual replicate.
