Extended Data Fig. 7: Spatiotemporal clustering of synaptic events excluding bAPs and comparing spine neck length.
From: Cortical response selectivity derives from strength in numbers of synapses
a, Relationship between spine pair distance and trial-to-trial correlation during visual stimulation, excluding stimulus trials with dendritic calcium events (Methods). Data are mean ± s.e.m (black). Also shown are shuffled correlations (grey dashed lines), data are s.e.m (n = 396 pairs from 5 cells from 3 animals). The grey data point denotes significant difference from shuffled correlations (P = 0.001, bootstrapped confidence interval, one-sided test). *P = 0.0023 (significantly different correlation distributions), Wilcoxon rank-sum two-sided test.b, Same as in a for synapse pairs with smaller spine head volume (<0.35 μm3; n = 132 pairs from 5 cells from 3 animals). c, Same as in a for synapse pairs with larger spine head volumes (>0.35 μm3; n = 86 pairs from 5 cells from 3 animals). The grey data point denotes significant difference from shuffled correlations (P = 0.016, bootstrapped confidence interval, one-sided test). *P = 0.0472 (significantly different correlation distributions), Wilcoxon rank-sum two-sided test.d, Relationship between spine pair distance and trial-to-trial correlation during visual stimulation. Note, these data are the same as shown in Fig. 4a. e, Same as in d for synapse pairs with smaller neck lengths (<1.75 μm; n = 112 pairs from 5 cells from 3 animals). f, Same as in d for synapse pairs with longer neck lengths (<1.75 μm; n = 106 pairs from 5 cells from 3 animals).
