Extended Data Fig. 4: Spine-soma functional similarity is uncorrelated with synaptic strength for spines with low residual correlation with dendritic signals.
From: Cortical response selectivity derives from strength in numbers of synapses
Relationships between the difference in orientation preference, direction preference, ocular dominance, and tuning correlation with spine head volume (blue), PSD area (red), and simulated spine-soma voltage attenuation (grey). Spines included were required to have rresidual < 0.2. Above each plot, correlation magnitude and p-value is shown. For orientation and direction preference differences, Circular-Linear correlation coefficient was calculated. For ocular dominance and tuning correlation, Spearman’s correlation coefficient was calculated. All significance tests are one-sided.
