Extended Data Fig. 7: Approximating I_syn from EPSP amplitude and transfer impedance.

a, For connections comprising a single synapse, I_syn can be estimated using Ohm’s Law from the experimentally recorded somatic EPSP amplitude and the simulated distance-dependent transfer impedance. b, When two synapses (A and B) were identified in electron microscopy, we assumed that the ratio of I_syn^A to I_syn^B followed the ratio of PSD^A to PSD^B, and that synaptic potentials sum linearly at the soma.