Extended Data Fig. 9: Highlighter plots of longitudinal SGA-derived Env amino acid sequences.
From: Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells
Highlighter plots were generated for six representative macaques that were depleted of CD8 and treated with N-803 using Env sequences from peak VL (red box), pre-ART (blue box) and reactivation (green box) time points. The Env sequence of the SIVmac239 clone used for infection is included as the master (reference) sequence in each plot. The position of N-linked glycosylation sites on the master sequence are indicated by pink circles. Each tick represents an amino acid difference from the master sequence, as indicated in the key. Blue diamonds indicate the loss of an N-linked glycosylation site.
