Extended Data Fig. 8: GATAD2A analyses. | Nature

Extended Data Fig. 8: GATAD2A analyses.

From: Occupancy maps of 208 chromatin-associated proteins in one human cell type

Extended Data Fig. 8

a, GATAD2A genome-wide ChIP–seq binding in HepG2 cells annotated by IDEAS state. b, Box plots showing expression level (RNA-seq TPM) of genes nearest sites with both GATAD2A and FOXA3 ChIP–seq peaks (green), genes nearest sites with FOXA3 peaks but no GATAD2A peaks (red), genes nearest sites with GATAD2A peaks but no FOXA3 peaks (blue), and GC-matched null regions for each CAP (grey). Boxes, middle quartiles; centre line, median; whiskers, 1.5 × IQR; n = 27,440 binding sites (GATAD2A + FOXA3), n = 10,658 binding sites (FOXA3 only), n = 13,706 binding sites (GATAD2A only), n = 37,073 binding sites (FOXA3 null matched), n = 40,441 binding sites (GATAD2A null matched). c, GO enrichments for genes with both GATAD2A and FOXA3 peaks. d, GO enrichments for genes with FOXA3 peaks but no GATAD2A peaks. e, GO enrichments for genes with GATAD2A peaks but no FOXA3 peaks. GO P value represents sample frequency probability.

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