Extended Data Fig. 1: CAP associations with annotated TSSs and IDEAS regions. | Nature

Extended Data Fig. 1: CAP associations with annotated TSSs and IDEAS regions.

From: Occupancy maps of 208 chromatin-associated proteins in one human cell type

Extended Data Fig. 1

a, The 208 ChIP–seq and CETCh–seq experiments plotted by number of peaks called in each experiment (x-axis) against fraction of peaks overlapping with any of 44,488 TSSs in the human genome (peaks ±3 kb from TSS). Selected individual CAPs are labelled. Solid line is linear regression through all points; dotted lines represent number of total TSS regions and maximum possible fraction of TSSs. b, IDEAS segmentation of HepG2 cell genome. Left, colour key for all IDEAS states; right, pie chart indicating fraction of HepG2 genome associated with each state. c, Clustering of 208 CAPs on the basis of chromatin state recapitulating the assigned cluster, with PC1 (63.50%), PC2 (16.51%) and PC3 (6.48%) variances explained. d, Left, distribution of regulatory regions by number of associated CAPs; right, distribution of horizontally matched sites by IDEAS state.

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