Extended Data Fig. 2: CAP associations with varying CpG and GC content.
From: Occupancy maps of 208 chromatin-associated proteins in one human cell type
a, Heat map and clustering of CAPs on the basis of association with low, intermediate, and high CpG content promoters (LCP, ICP, and HCP, respectively). All regions outside promoters are denoted as rest state. Annotation from Fig. 2a is shown, as are categories of direct DNA-binding factors (DBFs) and chromatin regulators or cofactors (CR/CF). b, Box plot of GC content of motifs for CAPs associating with promoters (n = 26), with both enhancers and promoters (n = 45), or with enhancers (n = 55). Centre line, median; boxes, 25th–75th percentiles; whiskers, 5th–95th percentiles.
