Extended Data Fig. 3: Motif analysis. | Nature

Extended Data Fig. 3: Motif analysis.

From: Occupancy maps of 208 chromatin-associated proteins in one human cell type

Extended Data Fig. 3

a, Cumulative fraction of called motifs in our data compared to motifs in the JASPAR 2016 vertebrate database as scored by Tomtom similarity E-value. b, Cumulative fraction of called motifs in our data compared to motifs in the JASPAR 2018 vertebrate database as scored by Tomtom similarity E-value. c, Cumulative fraction of called motifs in our data compared to motifs in the CIS-BP (build 1.02) Homo sapiens database as scored by Tomtom similarity E-value. d, Distribution of TF motifs by concordance (matching expected TF), discordance (matching different TF), and no match in the CIS-BP database. Stacked bar plots are coloured by main TF groups from previous unsupervised clustering. e, Distribution of TF motifs highly dissimilar to all motifs in CIS-BP (y-axis) and their median offset distance from the centre of peaks (x-axis). f, Stacked distribution of highly dissimilar motifs (no match; green) with similar (concordant; blue) and motif called for secondary factor (discordant; orange) and their median offset distances from the peak centre (x-axis).

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