Extended Data Fig. 3: Structural comparisons of the RBDs of SARS-CoV-2 and SARS-CoV and their binding modes to the ACE2 receptor.
From: Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor
a, Alignment of the SARS-CoV-2 RBD (core in cyan and RBM in red) and SARS-CoV RBD (core in orange and RBM in blue) structures. b, Structural alignment of the SARS-CoV-2 RBD–ACE2 and SARS-CoV RBD–ACE2 complexes. The SARS-CoV-2 RBD is shown in cyan and red, its interacting ACE2 is shown in green. The SARS-CoV RBD is shown in orange and blue, its interacting ACE2 is shown in salmon. The PDB code for the SARS-CoV RBD–ACE2 complex is 2AJF.
