Table 1 The hydrogen bonds and salt bridges at the SARS-CoV-2 RBD–ACE2 and SARS-CoV RBD–ACE2 interfaces
From: Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor
SARS-CoV-2 RBD | Length (Å) | ACE2 | Length (Å) | SARS-CoV RBD | |
|---|---|---|---|---|---|
Hydrogen bonds | N487(ND2) | 2.6 | Q24(OE1) | 2.9 | N473(ND2) |
K417(NZ) | 3.0 | D30(OD2) | |||
Q493(NE2) | 2.8 | E35(OE2) | |||
E37(OE1) | 3.4 | Y491(OH) | |||
Y505(OH) | 3.2 | E37(OE2) | |||
D38(OD1) | 3.0 | Y436(OH) | |||
Y449(OH) | 2.7 | D38(OD2) | 3.0 | Y436(OH) | |
T500(OG1) | 2.6 | Y41(OH) | 2.8 | T486(OG1) | |
N501(N) | 3.7 | Y41(OH) | 3.3 | T487(N) | |
G446(O) | 3.3 | Q42(NE2) | |||
Y449(OH) | 3.0 | Q42(NE2) | |||
Q42(OE1) | 2.7 | Y436(OH) | |||
Y489(OH) | 3.5 | Y83(OH) | 3.3 | Y475(OH) | |
N487(OD1) | 2.7 | Y83(OH) | 2.8 | N473(ND2) | |
Q325(OE1) | 3.8 | R426(NH2) | |||
E329(OE2) | 3.0 | R426(NH2) | |||
N330(ND2) | 2.8 | T486(O) | |||
G502(N) | 2.8 | K353(O) | 2.6 | G488(N) | |
Y505(OH) | 3.7 | R393(NH2) | |||
Salt bridges | K417(NZ) | 3.9 | D30(OD1) | ||
K417(NZ) | 3.0 | D30(OD2) | |||
E329(OE2) | 3.7 | R426(NH1) | |||
E329(OE1) | 3.9 | R426(NH2) | |||
E329(OE2) | 3.0 | R426(NH2) |
