Fig. 4: Antiviral activities of the drug leads against SARS-CoV-2.
From: Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors
a, The quantification of absolute viral RNA (vRNA) copies (per ml) in the supernatant at 72 h after infection, determined by qRT–PCR analysis. Data are mean ± s.e.m., n = 3 biological replicates. b, c, Dose–response curves for ebselen (b) and N3 (c) in the plaque-reduction assay. All data are shown as mean ± s.e.m., n = 4 biological replicates.
