Extended Data Fig. 5: The detergent-based assay for drug leads.
From: Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors
a–f, The IC50 values determined in the presence or absence of 0.01% Triton X-100, which show that detergent did not affect the results. g, Different concentrations of Triton X-100 notably affected IC50 curves for TDZD-8. All data are shown as mean ± s.e.m., n = 3 biological replicates.
