Extended Data Fig. 5: Effects of LbNOX expression on metabolic parameters during hyperinsulinaemic–euglycaemic clamp.
From: Hepatic NADH reductive stress underlies common variation in metabolic traits
a–k, Effects of LbNOX expression in HFD-fed mice using a 2.5 mU min−1 kg−1 insulin infusion during hyperinsulinaemic–euglycaemic clamp on body weight (a), basal glucose levels (b), clamp glucose levels (c), glucose infusion rate (d), whole-body glucose turnover (e), whole-body glycolysis (f), whole-body glycogen synthesis (g), lean mass (h), fat mass (i), WAT glucose uptake (j) and skeletal muscle glucose uptake (k). P values were determined using two-sided Student’s t-test. Data are reported as mean ± s.e.m. from n = 8 (luciferase) or n = 9 (LbNOX) mice.
