Extended Data Fig. 3: The rye mutation affects sleep-dependent memory.
From: Availability of food determines the need for sleep in memory consolidation
(a) Long-term memory is substantially lower in satiated short-sleeping rye mutants. Background iso31 line was used as control (two-sided t-test; n ≥ 8). (b) rye mutants form robust appetitive 24 h memory, similar to controls when kept starved (two-sided t-test; n ≥ 6). (c) Satiated rye mutants demonstrate no difference in sleep between trained and untrained groups. Total sleep in the ZT8-12 interval is depicted (two-sided t-tests were performed for each genotype to compare trained and untrained groups, followed by Bonferroni correction; n ≥ 31). Data are represented as mean ± s.e.m. Each data point in a memory experiment represents a group of flies and in a sleep experiment it depicts a single fly. Precise ‘n’ and ‘p’ values are in the Source Data. **P < 0.01; *P < 0.05.
