Extended Data Fig. 1: Homozygosity of the Ninj1 point mutation correlates with low responsiveness to LPS. | Nature

Extended Data Fig. 1: Homozygosity of the Ninj1 point mutation correlates with low responsiveness to LPS.

From: NINJ1 mediates plasma membrane rupture during lytic cell death

Extended Data Fig. 1

a, Ninj1 genotypes and screen phenotypes of mice derived from IGL03767. Identification numbers of screened mice are shown. G, generation. b, Nineteen SNV genotypes mutated in the pedigree and their phenotypes. c, Wild-type and IGL03767 Ninj1 genes. Exon 2 coding sequence is in uppercase and SNV mutation is in bold and highlighted with an asterisk. Grey boxes represent exons.

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