Extended Data Table 3 Residues that interact with Cl− in GltPh as captured with umbrella sampling simulations (and corresponding residues in EAAT1)

From: Glutamate transporters have a chloride channel with two hydrophobic gates

  1. Hydrophobic gate residues that are mutated in this study are shown in bold.
  2. *R477 of EAAT1 is found on TM8 and corresponds to R276, found in HP1 of GltPh.
  3. See refs. 20,29,30,35,37,38.
Back to article page