Extended Data Fig. 7: Distribution of core and variable synapses among neighbourhoods.

a, Membrane contacts of the L4, adult and M⁴ reference all have similar membrane contact profiles. For L4 and adult, only bilaterally conserved contacts are included. b, Synaptic contacts on M⁴ membrane contacts broken down by degree of synaptic contact reproducibility (ℂ¹, ℂ², ℂ³ and ℂ⁴). Most (56%) of conserved synapses (ℂ⁴) occur within clusters near the main diagonal, whereas variable synapses (ℂ¹) are spread across clusters. c, Gap-junction contacts on M⁴ membrane contacts broken down by degree of reproducibility (G¹, G², G³ and G⁴). For all matrices, row and column ordering is the same as the perturbed \(\tilde{{{\mathbb{M}}}^{4}}\) dataset (Extended Data Fig. 5i). Row and column colours correspond to final clusters assignments (Fig. 1d), where unclassified cells are coloured grey. Matrix element (i, j) corresponds to the fraction of cell i’s membrane contact with cell j, with rows normalized to sum to 1.