Extended Data Fig. 3: Core and variable model validations.
From: A multi-scale brain map derived from whole-brain volumetric reconstructions
a, b, Model fits for the reproducibility of Mδ, ℂδ and Gδ contacts, with membrane contact areas below (a) and above (b) the log-normalized mean (after thresholding; see Methods, Extended Data Fig. 2h). c, d, Reproducibility model fits of inter-cluster (c) and intra-cluster (d) Mδ, ℂδ and Gδ contacts. e, Reproducibility model fits for the complete Mδ, ℂδ and Gδ sets including contacts with the smallest 35% of membrane contact areas (results qualitatively similar to restricted dataset model fit in Fig. 2a; see Methods, ‘Generating reference graphs’). f, Reproducibility model fits for ℂδ excluding synaptic contacts scored in only one electron micrograph (Methods). g, Reproducibility model fits for ℂδ excluding synaptic contacts derived from non-reproducible postsynaptic partners of polyadic synapses (Methods). h, i, Reproducibility model fits for synaptic and gap-junction contact datasets scored by White et al.5 (h) and Witvliet et al.20 (i) limited to our M4 contacts. Black bars, empirical distributions used in this study; grey bars, other empirical distributions5,20; red bars, model fits for the empirical distributions. All data are presented as fractions of the empirical counts (n).
