Extended Data Fig. 8: ChIP–exo patterning reveals distinct local ssTF environments.
From: A high-resolution protein architecture of the budding yeast genome
a, Shown are strand-separated composite plots of 78 ssTFs bound at their cognate sites, and grouped by their meta-assemblage label (coloured borders, as defined in Extended Data Fig. 1c). Plots are oriented and centred by motif, and extend from −100 bp to +100 bp. Patterns were highly penetrant across individual sites for each ssTF (for example, see the lower right panel in Extended Data Fig. 2 for Reb1 and yeastepigenome.org for other ssTFs). b, ChIP–exo composite profiles of individual subunits of the Mediator complex at motifs that are bound by the ssTF Yrr1 (from −500 bp to +500 bp), showing consistency of patterning across Mediator subunits.
