Extended Data Fig. 1: Alignment of cDNA sequences of LILRB1-containing antibodies from donor A. | Nature

Extended Data Fig. 1: Alignment of cDNA sequences of LILRB1-containing antibodies from donor A.

From: Structural basis of malaria RIFIN binding by LILRB1-containing antibodies

Extended Data Fig. 1

Shown are the sequences of antibodies isolated from MDA (donor A). Cryptic splicing sites (GT and AG) are marked in bold blue; alternative splicing sites are marked in bold red. MDA8 has a different splicing site in the intron between LILRB1 exon 7 encoding the D3 domain and exon 8 encoding the D4 domain, resulting in insertion of a piece of intronic sequence (originated from the intron between exons 7 and 8) before exon 8.

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