Fig. 3: Sequence and structure of the chimpanzee, orangutan, and macaque chromosome 8 centromeres.
From: The structure, function and evolution of a complete human chromosome 8
a–d, Structure and sequence identity of the chimpanzee (H1) (a), chimpanzee (H2) (b), orangutan (c) and macaque (d) chromosome 8 centromeres. Each centromere has a mirrored organization consisting of four or five distinct evolutionary layers. The size of each centromeric region is consistent with microscopic analyses, showing increasingly bright DAPI staining with increasing centromere size. See Supplementary Figs. 10 and 11 for sequence identity heat maps plotted on the same colour scale. H1, haplotype 1; H2, haplotype 2. Scale bar, 1 μm.
