Extended Data Fig. 2: CHM13 chromosome 8 telomeres. | Nature

Extended Data Fig. 2: CHM13 chromosome 8 telomeres.

From: The structure, function and evolution of a complete human chromosome 8

Extended Data Fig. 2

a, Schematic showing the first and last megabase of the CHM13 chromosome 8 assembly. A dot plot of the terminal 5 kb shows high sequence identity among the last approximately 2.5 kb of the chromosome, consistent with the presence of a high-identity telomeric repeating unit. b, c, Number of TTAGGG telomeric repeats in the last 5 kb of the p-arm (b) and q-arm (c) in chromosome 8. The p-arm has a gradual transition to pure TTAGGG repeats over nearly 1 kb, whereas the q-arm has a very sharp transition to pure TTAGGG repeats that occurs over nearly 300 bp.

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