Fig. 5: Chromosome evolution among bats and other vertebrates.

a, Chromosome synteny maps across the species sequenced based on BUSCO gene alignments. Chromosome sizes (bar lengths) are normalized to genome size, to make visualization easier. Genes (lines) are coloured according to the human chromosome to which they belong; those on human chromosome 6 are highlighted in blue and other chromosomes are in lighter shades. The cladogram is from the TimeTree database⁷². b, Phylogenetic relationship of the mammalian species sequenced and their inferred chromosome EBR rates (breaks per Myr) on different branches. Red, higher rates than average (0.84); blue, lower than average. c, Summary of alignment, gene organization, and functional gene status surrounding a bat interchromosomal EBR involving the homologue of human chromosome 6. End of scaffold (S) or chromosome (Chr.) means that the breakpoint is located at a chromosome arm end; middle means that it is located within a scaffold or chromosome. Scale is relevant for human Chr. 6 only. Actual gene sizes in the non-human species may differ and were drawn to match the annotated human gene sizes for simplicity.