Extended Data Fig. 1: Phylogenetic tree of citrate-cleaving enzymes.
From: High CO2 levels drive the TCA cycle backwards towards autotrophy

Sequences were aligned using MUSCLE47, the phylogeny was calculated with IQtree48 using the maximum likelihood method (LG + R6 substitution model). The scale bar represents amino acid substitutions per site. Branch labels are SH-aLRT support/ultrafast bootstrap support (%) values from 1,000 replications. The sequences used to build the tree are available in Supplementary Table 11.