Extended Data Fig. 5: Cytokine analysis in BAL fluid post SARS-CoV-2 challenge.
From: Adjuvanting a subunit COVID-19 vaccine to induce protective immunity
a, Heat map showing expression of 24 cytokines measured in BAL fluid collected 1 week post SARS-CoV-2 challenge. b, Expression of Eotaxin-3 (CCL26), an eosinophil-recruiting chemokine known to be induced by the TH2 cytokine IL-13, and IL-5, a TH2 cytokine in the BAL fluid collected 1 week post challenge shows no significant increase in vaccinated animals compared to no vaccine controls. c, Abundance of cytokines known to be induced by SARS-CoV-2 infection in humans such as IL-8, MCP4, IL-6 and IFNγ in BAL collected 1 week post challenge. All the box plots show median, 25th and 75th percentiles and the whiskers show the range. N = 4 for control and O/W, 5 for all other groups.
