Extended Data Fig. 8: De novo genome reconstruction from present-day individuals of Mexican ancestry recovers 402 medium- and high-quality genomes, only 1 of which is a novel SGB.

Related to Fig. 2. a–d, CheckM⁷⁹ quality estimation of all de novo reconstructed microbial genomes (low-quality bins, n = 611; medium-quality bins, n = 256; high-quality bins, n = 146). Genomes were classified as low quality (completeness ≤ 50% or contamination > 5%), medium quality (90% ≥ completeness > 50% and contamination < 5%) or high quality (completeness > 90% and contamination < 5%). a, The number of bins that belong to each of the quality categories and classification of novel SGBs. b, Contamination and completeness distribution for the reconstructed genomes. c, Distribution of the number of contigs for each of the quality categories. d, Distribution of contig N50 values for each of the quality categories. e, GTDB-Tk²³ genus estimation for members of both the novel and the known Mexican SGBs. f, GTDB-Tk²³ species assignment for members of the known Mexican SGBs. In c, d, data are presented as box plots (middle line, median; lower hinge, first quartile; upper hinge, third quartile; upper whisker extends from the hinge to the largest value no further than 1.5× the interquartile range from the hinge; lower whisker extends from the hinge to the smallest value at most 1.5× the interquartile range from the hinge; data beyond the end of the whiskers are individually plotted outlying points).