Extended Data Fig. 10: A single-nucleus atlas of heart, kidney and liver COVID-19 tissues. | Nature

Extended Data Fig. 10: A single-nucleus atlas of heart, kidney and liver COVID-19 tissues.

From: COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets

Extended Data Fig. 10

ac, COVID-19 heart cell atlas. UMAP embedding of 40,880 heart nuclei (dots) (n = 18 donors, m = 19 specimens) coloured by Leiden resolution 1.5 clustering with manual post hoc annotations (a) or donors (c). b. Proportions of cell types (y axis) in each sample. df, COVID-19 kidney cell atlas. UMAP embedding of 33,872 kidney nuclei (dots) (n = 16, m = 16) coloured by clustering with manual post hoc annotations (d) or donors (f). e, Proportion of cells (y axis) in each sample. gi, COVID-19 liver cell atlas. g, i, UMAP embedding of 47,001 liver nuclei (dots) (n = 15, m = 16), coloured by clustering with manual post hoc annotations (g) or donors (i). h, Proportions of cell types (y axis) in each sample. jl, Automatic annotations. UMAP embeddings, coloured by predicted cell type labels by automatic annotation for heart (j), kidney (k) and liver (l).

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