Extended Data Fig. 6: Multiple sequence alignment of spike protein from a representative set of group 2b betacoronaviruses. | Nature

Extended Data Fig. 6: Multiple sequence alignment of spike protein from a representative set of group 2b betacoronaviruses.

From: Neutralizing antibody vaccine for pandemic and pre-emergent coronaviruses

Extended Data Fig. 6

SARS-CoV-2 Wuhan-1 spike protein numbering is shown. CD, connecting domain; CH, central helix; FP, fusion peptide; HR1, heptad repeat 1; HR2, heptad repeat 2; S1/S2, SARS-CoV-2 furin cleavage site; TM, transmembrane domain. ACE2 contact positions in SARS-CoV-2 (calculated from PDB coordinates 6MOJ and 6LZG) are highlighted in dark red.

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