Extended Data Fig. 8: Histology and immunohistochemistry of lung tissue collected seven days after SARS-CoV-2 WA-1 intratracheal and intranasal challenge.
From: Neutralizing antibody vaccine for pandemic and pre-emergent coronaviruses
a–c, Macaques were immunized thrice with RBD–scNP (a), twice with S-2P mRNA-LNP and once with RBD–scNP (b) or not immunized (c). Each column shows results from an individual macaque. The macaque identification number is shown above each column. Haematoxylin and eosin stain of lung sections are shown on the top row, with nucleocapsid immunohistochemistry shown on the bottom row for each macaque. Red arrows indicate site of antigen positivity. All images are shown at 10× magnification. Scale bars, 100 μm.
