Fig. 4: Characterization of BNT162b2-induced T cells on the single-epitope level.
From: BNT162b2 vaccine induces neutralizing antibodies and poly-specific T cells in humans
a, c, PBMCs obtained on day 1 (pre), day 29 and day 85 of three vaccinated participants (dose cohorts 10 μg, n = 1; 30 μg, n = 2) were analysed for CD8+ T cell epitope specificity (a) and phenotype (c) by flow cytometry (gating strategy in Supplementary Fig. 2). Peptide sequences above dot plots indicate pMHC class I multimer epitope specificity. Numbers above dot plots indicate the amino acid positions within S. b, Location of identified MHC class I-restricted epitopes within S.
