Extended Data Fig. 2: Solicited adverse events.
From: BNT162b2 vaccine induces neutralizing antibodies and poly-specific T cells in humans
a, b, Number of participants with local (a) or systemic (b) solicited adverse events. Participants were immunized with BNT162b2 on day 1 and day 22 (prime: n = 12 per dose cohort except for boost of the 1- and 100μg dose cohorts, for which n = 11); participants discontinued for non-vaccine-related reasons). Grey shading indicates number of participants at each time point. As per protocol, adverse events were recorded up to one week after each immunization (days 1–7 and 22–28) to determine reactogenicity; for some participants, data from 1–3 additional days of follow-up were available and are presented. Grading of adverse events was performed according to US Food and Drug Administration recommendations51.
