Extended Data Fig. 6: Cytokine and chemokine induction following SARS-CoV-2 infection.
From: In vivo monoclonal antibody efficacy against SARS-CoV-2 variant strains
Individual plots for cytokine and chemokine protein levels in the lungs of antibody-treated K18-hACE2 transgenic mice at 6 days after infection with the indicated SARS-CoV-2 strain (line indicates mean; n = 3 naive, n = 5 for all other groups of B.1.1.7- and N501Y-infected mice; n = 3 naive, 10 control, 5 for all other groups of Wash-B.1.351- and Wash-B.1.1.28-infected mice; one-way ANOVA with Dunnett’s test with comparison to control mAb: ns, not significant, ****P < 0.0001; all other P values are listed in Supplementary Table 5). Select cytokines and chemokines were used to generate the heat map in Extended Data Fig. 5.
