Extended Data Fig. 9: AHR1 exacerbates DSS colitis. | Nature

Extended Data Fig. 9: AHR1 exacerbates DSS colitis.

From: Adaptive immunity induces mutualism between commensal eukaryotes

Extended Data Fig. 9

a, Schematic of DSS colitis experiments. b, Histology images and scores for mice treated with no C. albicans or with TetO-AHR1 with and without aTC (no-Ca UT, no-Ca aTC and TetOn-AHR1 UT n = 7 mice per group, TetOff-AHR1 aTC n = 8 mice per group from two independent experiments). Data are mean ± s.d. c, DSS histology images for mice treated with no C. albicans or with wild-type C. albicans, ahr1∆/∆ C. albicans, TetOn-ALS1 ahr1∆/∆ C. albicans and TetOff-ALS1 ahr1∆/∆ C. albicans (aTC-treated). P values calculated using two-way ANOVA with Tukey’s test (b).

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