Extended Data Fig. 4: Differences in H2A.Z binding between UL subclasses and normal samples.
From: Deficient H2A.Z deposition is associated with genesis of uterine leiomyoma
log2 FC and average binding strength (normalized read concentration) were calculated on each H2A.Z peak region and are represented by a dot. a–d, MED12 (n = 3) (a), HMGA2 (n = 4) (b), FH (n = 4) (c) and OM (n = 3) (d) tumours were separately compared to all normal samples (n = 11). H2A.Z peak regions were stratified by five-state genome annotations from myometrium. States were annotated as bivalent TSS regions (TssBiv marked by both H3K4me3 and H3K27me3), active TSS regions (TssA marked by both H3K4me3 and H3K27ac), active chromatin outside TSS regions (OtherA marked by H3K27ac), repressed chromatin (Repr marked by H3K27me3) and other chromatin (Other).
