Extended Data Table 2 The genomic locations of candidate LMI070-induced exons and the frequency of events from RNA-seq datasets—continued

From: Regulated control of gene therapies by drug-induced splicing

  1. Columns (from left to right) indicate: 1. Exclusivity to LMI070 induction. 2. The gene ID containing the splicing events of interest. 3. The position of canonical splice junction (CJ). 4. The number of Intropolis RNA-seq datasets in which each canonical splice event was observed. 5. The total number of observations identified for each canonical splice site. 6. The position of junction 1 (J1) and the first LMI070-induced exon–exon junction (sorted by genomic position) connecting a canonical exon to a LMI070-induced pseudo exon. Columns 7 and 8 indicate the number and percentage of Intropolis datasets in which each J1 splice event was observed. Columns 9 and 10 indicate the number and percentage of total counts in which each J1 splice event was observed. 11. The position of junction 2 (J2) the second LMI070-induced exon–exon junction (sorted by genomic position) connecting a LMI070-induced pseudo exon to a canonical exon. Columns 12 and 13 list the number and percentage of Intropolis datasets in which the LMI070-induced splicing event was observed. Columns 14 and 15 indicate the total number and percentage of reads containing each junction in the Intropolis dataset.