Extended Data Fig. 7: Targeted resequencing in PD28690.
From: Extensive phylogenies of human development inferred from somatic mutations
Cladogram of PD28690 with contribution to 84 bulk samples (none derived from testes) as assessed through targeted resequencing of embryonic and spermatogonia-specific variants. The colour of the branch indicates the mean VAF of substitutions on that branch across all bulk samples. Nodes that gave rise to only seminiferous tubules are annotated with an asterisk. Branches coming from those nodes do not contribute to the bulk samples, confirming that the segregation of primordial germ cell lineages coincides with the observed branching point on the phylogenies.
