Fig. 5: Comparison of transcriptional responses with other vaccines.
From: Systems vaccinology of the BNT162b2 mRNA vaccine in humans
Circos plot of the overlap across vaccines in BTMs enriched on day 1. GSEA was performed on genes ranked by day 1 versus baseline t-statistic in each vaccine. Each segment of the circle represents one vaccine, and each point in a segment represents a single BTM. Bars in outer circle represent the NES of significantly enriched BTMs (FDR < 0.05). Lines connect BTMs with a significant positive enrichment shared between vaccines. Inner circle boxes and line colours represent the functional groups of the BTMs. ECM, extracellular matrix.
