Extended Data Fig. 4: Pre-existing autoantibodies and autocytokine antibodies do not change in vaccinated individuals.
From: Systems vaccinology of the BNT162b2 mRNA vaccine in humans
a–f, Bar plots (mean of two technical replicates) of representative patients with high baseline MFI autoantibodies for select antigens. a, Anti-RPP25 (Th/To). b, Anti-PM/Scl-75. c, Anti-SSB/La. d, Anti-PDC-E2. e, Anti-thyroperoxidase, TPO. f, Anti-thyroglobulin, TG. g–j, Bar plots (mean of two technical replicates) of representative patients with high baseline MFI autocytokine antibodies. Group bars represent antigens for baseline (black), day 21 (grey), and day 42 (white) time points. g, Individual 2012, anticytokine antibody measurements. h, Individual 2043, anticytokine antibody measurements. i, Individual 2052, anticytokine antibody measurements; j, Individual 2053, anticytokine antibody measurements.
