Extended Data Fig. 1: Additional type III-E family members and novel type III-D2 loci architecture and multiple alignment of representative orthologues.
From: Programmable RNA targeting with the single-protein CRISPR effector Cas7-11
a, Loci corresponding to listed accession IDs (see Supplementary Table 1), with key genes highlighted. CRISPR array symbols are not representative of the number of spacers in the array. b, Multiple alignment of representative Cas7-11 orthologues showing conservation of the residues involved in catalysis: D177, D429, D654, D745, D758, and E959. For the D177 alignment, members of the Csm3 family, which are Cas7-like proteins, are included for analysis of conserved residues (highlighted in grey).
