Extended Data Fig. 3: Subclustering markers for astrocytes, oligodendrocytes and OPC. | Nature

Extended Data Fig. 3: Subclustering markers for astrocytes, oligodendrocytes and OPC.

From: A lymphocyte–microglia–astrocyte axis in chronic active multiple sclerosis

Extended Data Fig. 3

ac, Subclustering UMAP plots for astrocytes, oligodendrocytes and OPC, and associated stacked violin plots depicting selected differentially expressed genes for each subcluster. d, Bar graph showing A1-marker30 expression (Z-scores relative to all astrocytes) for each astrocyte cluster. Most A1 markers were highly expressed in AIMS. UMAP, uniform manifold approximation and projection; OPC, oligodendrocyte progenitor cells; oligo, oligodendrocytes; AIMS, astrocytes inflamed in MS.

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