Extended Data Fig. 6: Two MIMS populations were identified through re-analysis of two published snRNA-seq MS datasets.
From: A lymphocyte–microglia–astrocyte axis in chronic active multiple sclerosis
a, snRNA-seq initial mapping (UMAP plot) and annotations based on the top differentially expressed genes in each cluster after re-analysis of raw data from Schirmer et al. 13 and Jäkel et al. 21. b, Immune cell nuclei were mapped onto our immune subclustering map. Most of the immune cell populations identified were seen also in the other datasets, including the two MIMS populations. UMAP, uniform manifold approximation and projection; MIMS, microglia inflamed in MS.
