Extended Data Fig 6: Overview of CPI1000+ cohort.
From: Using DNA sequencing data to quantify T cell fraction and therapy response
a, Cohort overview of the CPI1000+ dataset. b, Overview of samples in the CPI1000+ cohort excluding Snyder et al.49 and those with prior CPI treatment. c, ROC plot of GLM models for predicting CPI response (blue: clonal TMB, red: clonal TMB + TCRA T cell fraction, green: clonal TMB + CD8A expression). d, Cohort overview of the CPI lung dataset, red lines in upper panel reflect the median TCRA T cell fraction in patients with (0.10) or without (0.0070) a response to CPI, note that Tumour TCRA T cell fraction particularly in non-responders is often zero. e, Overview of patients in the CPI Lung cohort.
