Extended Data Fig. 9: Sequence alignments of the capsid proteins from different alphaviruses.
From: Structure of Venezuelan equine encephalitis virus with its receptor LDLRAD3
Sequence alignments of the capsid proteins from VEEV (AAB02517.1), WEEV (UniProt ID: P13897), EEEV (UniProt ID: P08768), ONNV (UniProt ID: O90369), SINV (UniProt ID: P03316), CHIKV (UniProt ID: Q5XXP3), MAYV (UniProt ID: Q8QZ72), and RRV (UniProt ID: P08491). Conserved residues are boxed and coloured red. Completely conserved residues are shown in white on a red background. Diamonds underneath the alignments indicate residues involved in the interactions between the VEEV capsid and E1. Red diamonds indicate residues that participate in the formation of hydrogen bonds at the VEEV capsid-E1 interfaces. Triangles underneath the alignments indicate residues involved in the interactions between the VEEV capsid and E2. Red triangles indicate residues that participate in the formation of hydrogen bonds at the VEEV capsid-E2 interfaces.
